Medical Definition
The World Health Organization defines obesity as a BMI of 30 or above. Class II obesity begins at 35, and class III (severe) obesity at 40. Waist circumference (≥102 cm in men, ≥88 cm in women) is an additional metabolic risk indicator.
Main Causes
Genetic and epigenetic predisposition
High-calorie, ultra-processed diets
Sedentary lifestyle
Sleep irregularity and chronic stress
Hormonal disorders (hypothyroidism, Cushing's syndrome)
Side effects of some medications
Psychosocial factors (eating disorders, depression)
Associated Conditions
Type 2 diabetes and insulin resistance
Hypertension and cardiovascular disease
Obstructive sleep apnoea
Non-alcoholic fatty liver disease (NAFLD)
Joint pain and osteoarthritis
Polycystic ovary syndrome and infertility
Certain cancers (breast, colon, endometrium)
Why It Matters
Obesity is a treatable chronic disease. Early diagnosis, lifestyle modification, medical therapy when appropriate, and bariatric surgery in suitable patients can substantially improve long-term health outcomes.
References
- World Health Organization — Obesity and overweight fact sheet
- International Diabetes Federation — Metabolic Syndrome Criteria
Last updated: 28.06.2026 · Medical content: Op.Dr.Gökhan ATEŞ